Summary: Aims. The objectives of this study were to determine the burnout level at work and the level of compassion on the whole scale and on individual sub-scales (avoiding indifference, humanity, focused awareness and kindness) in nurses/technicians and examine the relationship of burnout at work with the degree of compassion for others and socio-demographic characteristics of the subject. Methods. The study involved 130 nurses/technicians employed at Clinical Hospital Centre Split with an average age of 33.56 years and 12.5 years of service, of which 88.5% were female. The largest number of respondents were in marital/non-marital union at the time of the study (56.2%), about 40% were not married, while the smallest number of respondents were divorced or their partner died (6.2%). About 44% of the respondents have no children, while most of the others have one or two children. About 11% of respondents have three or more children. The following questionnaires were used: Workplace Burnout Intensity Questionnaire, Compassion Scale and General data questionnaire Results. Respondents estimate their own compassion for patients with moderate to high grades, where the greatest exception is the compassion scale – avoiding indifference with a standard deviation of 3.49. The level of burnout is expressed in a moderate degree with an average score of 30.37 and a deviation of 8.77. Subjects in different categories of marital status differ significantly from one another (F = 4.69, p = 0.011), where people who are unmarried experience the highest level of burnout (M = 33.27, SD = 9.34). There is a significantly higher level of burnout for single subjects than married ones (p = 0.011), while amongst other groups a statistically significant difference has not been established. No significant difference of burnout between males and females was found (p = 0.34). The age of the subject is significantly positively related to years of service and the number of children. Subjects who are of a older chronological age have more years of service and more children than younger subjects. The dimensions of compassion (avoiding indifference, humanity, focused awareness and kindness) are interconnected to a moderate degree and are significantly positively linked to the overall result on the compassion scale. Thus, nurses who focus on patients, treat them humanely, treat them with kindness and do not show apathy generally score higher points on the compassion scale. Nurses who don't show apathy, who focus more on patients and use empathetic health care, have lower levels of burnout at work. Regression coefficient indicates that based on the compassionate care shown, the level of burnout can be predicted, which suggests that compassionate care has a protective effect towards burnout at work (β = -0.24, p < 0.008). Higher levels of burnout at work can be predicted in healthcare professionals who are less focused on their patients, who have fewer children of their own and those with more work experience. These results indicate the combined impact of personal factors and patient relationships on the likelihood of burnout at work. Conclusion. Nurses/technicians experience moderate burnout at work and moderate to high levels of compassion. Higher levels of burnout at work are experienced by health professionals who are less focused on their patients, who have fewer children of their own and have more seniority.