Aim of research: To analyze the indicators tested by means of a questionnaire on health-related quality of life in groups of women suffering from osteoporosis with/without pathological bone fracture pre/post medical gymnastics physical treatment in order to get an insight into differences between the groups, based on comparison of the results obtained by the research. Methods: The main source of information is the 36-Item Short Form Health Survey (SF-36). The survey was conducted from April to August 2016 in Split University Medical Center, Department of Physical Medicine, Rehabilitation and Rheumatology. The total number of women suffering from osteoporosis included in the survey is 60 (30 with pathological bone fracture and 30 without it). Results: The results obtained by the 36-Item Short Form Health Survey (SF-36) show a significant improvement in terms of quality of life related to both physical and emotional health as well as the ability to perform activities of daily living (ADL) after a 10 day physical therapy treatment such as medical gymnastics. On the basis of empirical P values less than 5%, it can be concluded that there is a statistically significant upward trend in the quality of life indicatoors regarding all observed health dimensions. The change of values in more than 75% of patients refers to the upward trend in all observed health dimensions. On the basis of empirical P values 0, 028 (limitations due to physical problems) and 0, 036 (health change), the following can be concluded. Firstly, there is a statistically significant difference in the two aforementioned health dimensions among the patients of both groups. Secondly, the therapy which was used had different impacts on the observed groups. Conclusions: The 36-Item Short Form Health Survey (SF-36) used in this research is designed for use not only in research but also in clinical practice, health policy evaluations, and general population surveys. Quantitative data analysis regarding subjective health and quality of life estimation indicates an increase of functional abilities as well as feeling good sensation in all observed health dimensions within both groups of patients after a physical therapy treatment. The research results illustrate the value and importance of medical gymnastics in achieving significant improvement regarding activities of daily living (ADL).