Prenatal care and diagnosis allows prevention, recognition and treatment of all diseases and patological conditions which may endanger the pregnancy. Prenatal care has to be systematic and cover all pregnant women, so each one of them should go at least once to their gynecologist during the first 8 weeks of pregnancy. Gynecologist will use ultrasound, bimanual examination, as well as all other necessary researches. Ultrasound, as an indispensable diagnostical tool in prenatal diagnosis, takes an important place. Ultrasound allows the early discoveries of congenital malformations and estimates with high accurancy a neat or disrupted fetal growth. Another thing is that with biophysical tests and doppler measurements provides active supervision over the fetus condition. Non-invasive prenatal testing is predicted for all pregnant women, regardless of their age, i.e. for those women who do not have family genetic history, but allready have a child with congenital malformation etc. Very important role in informing pregnant women about prenatal testing, as well as about the pregnancy has a midwife. She has got a significant role because midwife is the one who will be the closest to a pregnant women during the pregnancy.