Research aim: the main aim of this research was to examine the connection between nurses/tehnicians education and the places where nurses/tehnicians work with self- assessed knowledge on communication skills and attitudes to work with a depressed patient with the help of questionnaire responses. Research methods: the study included 63 nurses/tehnicians from Oncology and Radiotherapy Clinic, Psychiatric Clinic and Surgery Clini on Clinical Hospital Center in Split. Respondents were interviewed in the period of August to September 2017. We collected data about sociodemographic characteristics and attitudes of respondents and self- assessments of their communication skills in the work with a depressed patients. Results: nurses and tehnicians rated their communication skills with a high grade of 4. The workplace of nurses/tehnicians was significantly connected with self- assessed knowledge of communication skills. Nurses from the Oncology and Radiotherapy Clinic evaluated themselfs to the highest scores while the nurses from the Surgery Clinic continuously provided themselfs with the worst grades which proves responds to 6 particles (P≤0.041). Furthermore, the type of clinic on which nurses/tehnicians work was significantly associated with attitudes of their work with depressed patient on all tested particles (P≤0.041). Nurses/tehnicians from the Psychiatric Clinic were most aware of the complexity of depression and very fond of the idea of additional education on working with such patients while nurses from the Oncologi and Radiotherapy Clinic largely thought that such education was not necessary. There was no correlation between the formal level of education and self- assessed knowledge and attitudes. Conclusion: although nurses/tehnicians evaluate their knowledge of communication skills by high rating, it is not clear do the patients experience these skills equally. Differences in self- assesed knowledge and attitudes between different clinics point to the need for additional education on working with depressed patients on those non- psychiatric clinics.