BACKGROUND: Among the most common diseases of modern era are cardiovascular ailments which are highly positioned on mortality scale in Europe, especially in Croatia, where they are leading cause of death. Accordingly, it is necessary to find a solution through systematic and continuous efforts in prevention, early recognition and treatment of cardiac diseases; among that through quality education of healthcare providers and the general population. We're finding out how educated is general population, excluding health care workers, through this scientific research in which students were tested based on their knowledge of resuscitation. AIM: Assess students' knowledge of cardiopulmonary resuscitation; to examine an impact of CPR educations on students' knowledge level; compare the knowledge level of students of University of Split and University of Mostar; to determine students' interest in further CPR training. MATERIAL AND METHODS: Quantitative descriptive research was conducted. The target group were students of non-medical studies of the University of Mostar and the same population of students of the University of Split, a 123 respondents in total. In order to collect the data, author of research provided a specifically formulated questionnaire, made in electronic form. The data was collected in August 2019. RESULTS: The conclusion which was made after survey shows that there was no statistically significant difference between the level of knowledge of the students of the University of Split and the University of Mostar; the existence of statistically significant differences between the level of knowledge and participation in education is confirmed; there isn't negative correlation between the level of knowledge about cardiopulmonary resuscitation and the absence of education; positive level of interest for further CPR training has been confirmed. CONCLUSION: A statistical analysis of the obtained results revealed that students of non-medical studies show an unsatisfactory level of knowledge on the questions raised and in a total of 3 questions out of 10, the percentage of inaccurate responses was notably higher. Achieved results confirm the importance and effectiveness of additional education in the field of emergency medicine and resuscitation, which in accordance with the requirements and interest could produce important projects and manifestations in the future in order to educate the general population-not only on this, but also on other relevant topics important for human health and promptly reacting when it's endangered.