Gastrointestinal bleeding is defined by the appearance of blood in the digestive system. Manifested by Melena (black, tarry faces), hematemesis (vomiting of blood) and haematochesia (passing visible light red or dark red blood from the rectum). Symptoms and signs of bleeding depend on the size of the volume of blood lost. Bleeding from the gastrointestinal tract can be divided into bleeding from the upper and lower parts. Treitz ligament separates the upper gastrointestinal bleeding (esophagus, stomach and duodenum) from the lower (ileum and colon) (4). AIM OF RESEARCH The aim of this BSc Thesis is to explain the important role of nurses in health care of patients with bleeding from the upper gastrointestinal tract, show health care problems and give an overview of the causes, symptoms and typical diagnostic methods of gastrointestinal bleeding from the upper gastrointestinal tract. It is also necessary to show the results of statistical processing of data available for patients who are diagnosed in 2013 with acute gastrointestinal bleeding received at the Intensive Care Unit of the Department of Gastroenterology and Hepatology, Clinic of Internal Medicine, Hospital Centre Split. METHODS Data from the protocols of the Intensive Care Unit of the Clinic for Internal Medicine, as well as release protocols from the Office of the Department of Internal Medicine, Hospital Centre Split have been collected and statistically analyzed for the period from January 1 to December 31, 2013. All patients who were admitted with the diagnosis of acute gastrointestinal bleeding were taken in account. RESULTS It was established that 419 patients have been admitted with the diagnosis of acute bleeding in the Intensive Care Unit of the Department of Gastroenterology and Hepatology at the Clinic for Internal Medicine. Of the total number of patients, there were 298 men which amounts to 71.1%, and 121 women or 28.9%. The average age of the patients received was 69.3 years and the average length of hospital stay 8.7 days. During hospitalization, 55 patients died, which amounts to 13.1% of the total number of patients. Trend of increasing mortality with age were established in both populations. Diagnosis of patients admitted indicate that only a small portion (75 patients) bleed from the lower part of the digestive system, while the majority (344 patients), bleed from the upper gastrointestinal tract. Results of diagnosis points to bleeding from duodenal ulcers as the most important source of bleeding (26.2%), followed by gastric ulcer (13.4%), while esophageal varices (4.7%) and Melory-Weiss syndrome (2%) are of minor importance.