Lumbar pain syndrome is a clinical entity defined as pain, muscle tension and discomfort that can be felt in the back area, between the lower rib arch and the lower gluteal sulcus, with or without the spread of pain in the leg. It is a major public health problem, but also a challenge in treatment. The most common, nonspecific low back pain is pain in the lumbar region that cannot be explained by a known specific pathology. Rehabilitation and application of various modalities of physical therapy is an integral part of the treatment of patients with lumbar pain syndrome. It is performed with the aim of reducing pain and muscle tension, increasing the mobility of the spine, improving functional status and quality of life. The outcome of treatment is significantly influenced by patient education. It is important that the patient knows the main causes of low back pain, the proper performance of daily life activities and therapeutic exercise programs, and the importance of adjusting the workplace and living space. Dynamic neuromuscular stabilization is a functional-rehabilitation method of deep stabilization of the locomotor system, which is based on the developmental kinesiology of the child in the first year of life, on the principles of neurophysiology and biomechanics. With today's sedentary lifestyle, a person loses healthy patterns of movement, and changes them to non-physiological ones that cause pain. Thanks to the proven effectiveness in the prevention and rehabilitation of lumbar pain syndrome, DNS is increasingly being introduced into rehabilitation programs. The aim of this study was to demonstrate the effectiveness of dynamic non-muscular stabilization in the rehabilitation of patients with lumbar pain syndrome. Conducted DNS therapy and patient education resulted in improved functional status and reduced pain. An important thing to make the patient aware of is the need for regular exercise and maintenance of activities to reduce pain and improve quality of life.