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undergraduate thesis
Usporedba seroloških testova i PCR analize u procjeni zaraženosti Corona virusom
2021. urn:nbn:hr:176:933813
Tokalić, Antonela
University of Split
University Department of Health Studies
Chair of Medical Laboratory Diagnostics

Cite this document

Tokalić, A. (2021). Usporedba seroloških testova i PCR analize u procjeni zaraženosti Corona virusom (Undergraduate thesis). Retrieved from https://urn.nsk.hr/urn:nbn:hr:176:933813

Tokalić, Antonela. "Usporedba seroloških testova i PCR analize u procjeni zaraženosti Corona virusom." Undergraduate thesis, University of Split, University Department of Health Studies, 2021. https://urn.nsk.hr/urn:nbn:hr:176:933813

Tokalić, Antonela. "Usporedba seroloških testova i PCR analize u procjeni zaraženosti Corona virusom." Undergraduate thesis, University of Split, University Department of Health Studies, 2021. https://urn.nsk.hr/urn:nbn:hr:176:933813

Tokalić, A. (2021). 'Usporedba seroloških testova i PCR analize u procjeni zaraženosti Corona virusom', Undergraduate thesis, University of Split, University Department of Health Studies, accessed 22 March 2023, https://urn.nsk.hr/urn:nbn:hr:176:933813

Tokalić A. Usporedba seroloških testova i PCR analize u procjeni zaraženosti Corona virusom [Undergraduate thesis]. Split: University of Split, University Department of Health Studies; 2021 [cited 2023 March 22] Available at: https://urn.nsk.hr/urn:nbn:hr:176:933813

A. Tokalić, "Usporedba seroloških testova i PCR analize u procjeni zaraženosti Corona virusom", Undergraduate thesis, University of Split, University Department of Health Studies, Split, 2021. Available at: https://urn.nsk.hr/urn:nbn:hr:176:933813

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Metadata
TitleUsporedba seroloških testova i PCR analize u procjeni zaraženosti Corona virusom
Title (english)THE COMPARISON OF SEROLOGICAL TESTS AND PCR ANALYSIS IN THE ASSESSMENT OF CORONA VIRUS INFECTION
AuthorAntonela Tokalić
MentorDavorka Sutlović (mentor)
MentorSendi Kuret (sumentor)
Committee memberEsma Čečuk-Jeličić (predsjednik povjerenstva)
Committee memberAntonela Matana (član povjerenstva)
Committee memberDavorka Sutlović (član povjerenstva)
GranterUniversity of Split
University Department of Health Studies
(Chair of Medical Laboratory Diagnostics)
Split
Defense date and country2021-07-01, Croatia
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Abstract
Cilj: Cilj ovog rada je prikazati serološke i molekularne testove za dijagnostiku SARS-CoV-2 infekcije te usporediti njihovu osnovnu zadaću, prednosti i nedostatke u procjeni zaraženosti korona virusom. Materijal i metode: Identifikacija SARS-CoV-2 provodi se dvjema metodama: molekularnom - RT-qPCR koja otkriva prisutnost samog virusa i serološkim - testovima koji dokazuju kontakt s virusom otkrivanjem antitijela koja su nastala nakon preboljenja bolesti ili nakon cijepljenja. Za RT-qPCR metodu materijal za analizu je bris uzet iz nosa ili grla , a za serološko testiranje uzima se uzorak krvi. Rezultati: Pozitivan PCR test znači da osoba koja se testira ima virus koji uzrokuje COVID-19. Pozitivan test na antitijela znači da je osoba koja se testirala u prošlosti vjerojatno zaražena COVID-19 i da su u njezinom imunološkom sustavu nastala antitijela. Zaključak: PCR testovima se identificira prisustvo samog virusa organizmu kako bi se utvrdilo postoji li aktivna infekcija SARSCoV-2.Serološkim testiranjem se utvrđuje postojanje antitijela protiv SARS-CoV-2 u krvi kako bi utvrdila je li netko bio zaražen. S obzirom da PCR i serološko testiranje imaju različite prednosti i ograničenja kada se međusobno uspoređuju , najbolje je korištenje obiju metoda u pružanju najboljih rezultata.
Abstract (english)
Objectives: The aim of this paper is to present serological and molecular tests for the diagnosis of SARS-CoV-2 infection and to compare their basic task, advantages and disadvantages in the assessment of coronavirus infection. Material and methods: Identification of SARS-CoV-2 is performed by two methods: molecular - RT-qPCR which detects the presence of the virus itself and serological - tests that prove contact with the virus by detecting antibodies formed after overcoming the disease or after vaccination. For the RT-qPCR method, the material for analysis is a swab taken from the nose or throat, and for serological testing, a blood sample is taken. Results: A positive PCR test means that the person being tested has the virus that causes COVID-19. A positive antibody test means that the person being tested was likely infected with COVID-19 in the past and that their immune system developed antibodies to try to fight it off Conclusion: PCR tests identify the presence of the virus itself in the body to determine if there is an active SARSCoV-2 infection. Serological testing determines the presence of antibodies against SARS-CoV-2 in the blood to determine if someone is infected. Since PCR and serological testing have different advantages and limitations when compared with each other, it is best to use both methods in providing the best results.
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:176:933813
Study programmeTitle: Medical Laboratory Diagnostics (university/undergraduate)
Study programme type: university
Study level: undergraduate
Academic / professional title: sveučilišni prvostupnik/ prvostupnica (baccalaureus/ baccalaurea) medicinske laboratorijske dijagnostike (sveučilišni prvostupnik/ prvostupnica (baccalaureus/ baccalaurea) medicinske laboratorijske dijagnostike)
Type of resourceText
File originBorn digital
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2021-07-01 18:19:44