AIM: To compare the attitudes of patients suffering from schizophrenia towards therapy with regard to the acute phase of the disease and stable remission. METHODS: The research was conducted from March to July 2023. in the Split Clinical Hospital Center (KBC Split). A total of 60 respondents participated, 30 of them are in the remission phase and 30 in the acute phase. The questionnaire includes sociodemographic data, data on lifestyle habits and attitudes about therapy. It consists of 13 open and closed questions and 10 questions related to attitudes about therapy. RESULTS: The obtained data confirmed a more positive attitude towards the therapy of the subjects in the phase of stable remission than those in the acute phase. The hypothesis that patients in remission have more positive attitudes towards medication was confirmed. The hypothesis that patients in the remission phase are older than patients in the acute phase was confirmed. Differences in age are shown by the mean value, which confirms that the patients in remission are older than the patients in the acute phase. CONCLUSION: From the obtained data, we can conclude that older patients have more positive attitudes about taking medication and therapy, especially those who are in a phase of stable remission. The results are in line with expectations. There is no significant difference in the gender of the respondents. Further research related to specific negative attitudes and with a larger number of respondents of different ages is needed.