Abstract | veličine stenta i aorte i utjecaj duljine proksimalne landing zone na ishode liječenja. Ishodi su mortalitet i pojava endoleaka. Ispitati utjecaj patologije torakalne aorte na vrijeme od dijagnoze do ugradnje TEVAR-a.
Materijali i metode: Radi se o retrospektivnom istraživanju. Ispitanici su svi bolesnici koji su podvrgnuti interventnom radiološkom zahvatu ugradnje TEVAR-a u periodu od siječnja 2016 do svibnja 2022. godine. Istraživanje je provedeno na Kliničkom zavodu za dijagnostičku i intervencijsku radiologiju KBC-a Split.
Rezultati: Pacijenti su u rasponu dobi od 22 do 71 godine, a medijan dobi je 57,5 godina. Od ukupnog broja pacijenata hitnom zahvatu podvrgnuto je njih 7 (43,75%) zbog politraume, a 9 (56,25%) pacijenata imalo je druge indikacije za ugradnju TEVAR-a. Od ukupnog broja pacijenata danas je živo 12 (75%), a preminula su 4 (25%) pacijenta. Komorbiditete ( šećerna bolest ili arterijska hipertenzija) imalo je 7 (43,75%) pacijenata, dok je 9 (56,25%) pacijenata bilo bez komorbiditeta. Kod preživljenja pacijenata i pojava endoleaka u odnosu na prisutnost politraume, komorbiditeta i aneurizme nije dokazana statistički značajna povezanost. Za analizu utjecaja kronološke dobi (pe=0,32,pžp= p=0,48), omjera veličine stent grafta i aorte proksimalno (pe= p=0,43,pžp= p=0,48) i distalno (pe= p=0,91,pžp=0,48), veličine proksimalne landing zone (pe= p=0,32,pžp= p=0,48) u odnosu na pojavu endoleaka i preživljenje pacijenta identificirano je da ne postoji statistički značajna razlika. Kada smo određivali statistički značajnu razliku u vremenu čekanja na ugradnju TEVAR-a između politraumatiziranih pacijenata i onih koji to nisu dobili smo da je p=0,12 i da ne postoji statistički značajna razlika.
Zaključak: Nema razlike između dobi,komorbiditetai politraume, utjecaja omjera veličine stenta i aorte i utjecaja veličine proksimalne landing zone u odnosu na pojavu smrtnog ishoda i endoleaka.studija je pokazala da nema razlike u vremenu ugradnje TEVAR-a kod politraumatiziranih pacijenata ionih koji to nisu. Zaključke treba uzeti s rezervom s obzirom da se radi o retrospektivnoj studiji sa malim uzorkom pacijenata, ograničenim pristupom povijesti bolesti i nemogućnosti praćenja pacijenata nakon zahvata. Svakako je potrebno daljnje istraživanje na većem uzorku pacijenata. |
Abstract (english) | Research objective: To examine the influence of age, comorbidity and polytrauma on treatment outcomes. To determine the influence of the size ratio of the stent to the aorta and the influence of the length of the proximal landing zone on treatment outcomes. Outcomes are mortality and occurrence of endoleaks. To examine the influence of thoracic aortic pathology on the time from diagnosis to TEVAR implantation.
Materials and methods: This is a retrospective study. The respondents are all patients who underwent interventional radiological procedures for the installation of TEVAR in the period from January 2016 to May 2022. The research was conducted at the Clinical Institute for Diagnostic and Interventional Radiology of KBC Split.
Results: Patients range in age from 22 to 71 years, and the median age is 57.5 years. Of the total number of patients, 7 (43.75%) underwent emergency surgery due to polytrauma, and 9 (56.25%) patients had other indications for TEVAR implantation. Of the total number of patients, 12 (75%) are alive today, and 4 (25%) patients have died. 7 (43.75%) patients had comorbidities (diabetes or arterial hypertension), while 9 (56.25%) patients had no comorbidities. In terms of patient survival and the occurrence of endoleaks in relation to the presence of polytrauma, comorbidities and aneurysms, no statistically significant correlation has been demonstrated. To analyze the influence of chronological age (pe=0.32, pžp= p=0.48), the size ratio of the stent graft and the aorta proximally (pe= p=0.43, pžp= p=0.48) and distally (pe= p=0.91, pžp=0.48), the size of the proximal landing zone (pe= p=0.32, pžp= p=0.48) in relation to the occurrence of endoleaks and patient survival, it was identified that there is no statistically significant difference . When we determined a statistically significant difference in the waiting time for TEVAR implantation between polytraumatized patients and those who were not, we found that p=0.12 and that there is no statistically significant difference.
Conclusion: There is no difference between age, comorbidity and polytrauma, the influence of the ratio of the size of the stent to the aorta and the influence of the size of the proximal landing zone in relation to the occurrence of death and endoleak. The study showed that there is no difference in the time of TEVAR implantation in polytraumatized patients and those who are not . Conclusions should be taken with a grain of salt, given that this is a retrospective study with a small sample of patients, limited access to medical history, and the inability to follow up patients after the procedure. Further research on a larger sample of patients is certainly needed. |