prikaz prve stranice dokumenta Molekularna dijagnostika spolno prenosivih infekcija u žena
  Download
PDF 700.59 KB
undergraduate thesis
Molekularna dijagnostika spolno prenosivih infekcija u žena
2024. urn:nbn:hr:176:764111
Radjenović, Lucija
University of Split
University Department of Health Studies

Cite this document

Radjenović, L. (2024). Molekularna dijagnostika spolno prenosivih infekcija u žena (Undergraduate thesis). Split: University of Split. Retrieved from https://urn.nsk.hr/urn:nbn:hr:176:764111

Radjenović, Lucija. "Molekularna dijagnostika spolno prenosivih infekcija u žena." Undergraduate thesis, University of Split, 2024. https://urn.nsk.hr/urn:nbn:hr:176:764111

Radjenović, Lucija. "Molekularna dijagnostika spolno prenosivih infekcija u žena." Undergraduate thesis, University of Split, 2024. https://urn.nsk.hr/urn:nbn:hr:176:764111

Radjenović, L. (2024). 'Molekularna dijagnostika spolno prenosivih infekcija u žena', Undergraduate thesis, University of Split, accessed 20 December 2024, https://urn.nsk.hr/urn:nbn:hr:176:764111

Radjenović L. Molekularna dijagnostika spolno prenosivih infekcija u žena [Undergraduate thesis]. Split: University of Split; 2024 [cited 2024 December 20] Available at: https://urn.nsk.hr/urn:nbn:hr:176:764111

L. Radjenović, "Molekularna dijagnostika spolno prenosivih infekcija u žena", Undergraduate thesis, University of Split, Split, 2024. Available at: https://urn.nsk.hr/urn:nbn:hr:176:764111

Please login to the repository to save this object to your list.
Metadata
TitleMolekularna dijagnostika spolno prenosivih infekcija u žena
Title (english)Molecular diagnosis of sexually transmitted infections in women
AuthorLucija Radjenović
MentorSendi Kuret (mentor)
Committee memberEsma Čečuk-Jeličić (predsjednik povjerenstva)
Committee memberDavorka Sutlović (član povjerenstva)
Committee memberSendi Kuret (član povjerenstva)
GranterUniversity of Split
(University Department of Health Studies)
Split
Defense date and country2024-07-17, Croatia
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Abstract
Cilj ovog rada je prikazati važnost molekularne dijagnostike bakterija i virusa kod spolno prenosivih infekcija radi odabira odgovarajuće terapije u njihovom liječenju. Materijali korišteni za analizu uključuju vaginalne briseve uzete od pacijentica sumnjivih na spolno prenosive infekcije. Opisan je postupak uzorkovanja, izolacije nukleinske kiseline te umnažanja i otkirvanja patogena uz pomoć komercijalno dostupnih kitova. Rezultati istraživanja pokazali su da je real-time PCR (RT-PCR) metoda visoko osjetljiva i specifična za detekciju najčešćih uzročnika spolno prenosivih infekcija kod žena. Sve analizirane uzorke uspješno su identificirani uzročnici kao što su HPV, Chlamydia trachomatis, Mycoplasma genitalium, Mycoplasma hominis, Ureaplasma urealyticum i Trichomonas vaginalis. Molekularne metode, posebno RT-PCR, predstavljaju zlatni standard u dijagnostici spolno prenosivih infekcija zbog svoje visoke osjetljivosti, specifičnosti i brzine. Njihova primjena omogućuje rano otkrivanje i ciljano liječenje infekcija, što značajno poboljšava ishode liječenja i smanjuje rizik od komplikacija.
Abstract (english)
The aim of this paper is to demonstrate the importance of molecular diagnostics of bacteria and viruses in sexually transmitted infections (STIs) for the selection of appropriate therapy in their treatment. The materials used for the analysis include vaginal swabs taken from patients suspected of having STIs. The procedures for sampling, nucleic acid isolation, and pathogen detection through commercially available kits are described. The research results showed that the real-time PCR (RT-PCR) method is highly sensitive and specific for detecting the most common causes of STIs in women. Pathogens such as HPV, Chlamydia trachomatis, Mycoplasma genitalium, Mycoplasma hominis, Ureaplasma urealyticum, and Trichomonas vaginalis were successfully identified in all analyzed samples. Molecular methods, particularly RT-PCR, represent the gold standard in the diagnosis of sexually transmitted infections due to their high sensitivity, specificity, and speed. Their application enables early detection and targeted treatment of infections, which significantly improves treatment outcomes and reduces the risk of complications.
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:176:764111
Study programmeTitle: Undergraduate University Study Programme of Medical Laboratory Diagnostics
Study programme type: university
Study level: undergraduate
Academic / professional title: sveučilišni prvostupnik/prvostupnica (baccalaureus/baccalaurea) medicinske laboratorijske dijagnostike (sveučilišni prvostupnik/prvostupnica (baccalaureus/baccalaurea) medicinske laboratorijske dijagnostike)
Type of resourceText
File originBorn digital
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2024-07-17 08:48:11