Polytrauma is a condition in which at least two organs or anatomical regions are injured and in which at least one of the injuries is life-threatening for the injured person. Nowadays, traffic accidents are the most common cause of polytrauma. Quick and accurate diagnosis plays a key role in treating polytraumatized patients. Among other things, diagnostic treatment includes radiological procedures, and CT imaging is most often used because it provides important diagnostic information in a short period of time that helps in planning further treatment and therapy. Full-body CT is most often performed after the primary examination and when the patient is in a stable condition. Some studies have shown that patients scanned according to this protocol have a higher survival rate. Indications for a full-body CT scan include a high speed motor vehicle collision, a motorcycle crash, a fall from height more than 2 meters, an abnormal FAST (Focused Assessment With Sonography In Trauma), or trauma chest or pelvis x-ray and abnormal vital signs, but can also vary from hospital to hospital. A typical whole-body CT protocol consists of the following phases: head without contrast, cervical spine without contrast, contrast enhanced chest (arterial phase) and contrast enhanced abdomen (portal venous phase). Despite its disadvantages, such as the high dose of radiation, CT remains an indispensable diagnostic method for detecting injuries when treating patients with polytrauma.