Muscle spasticity is a common neurological symptom in patients with multiple sclerosis, characterized by involuntary, rapid and sometimes painful muscle spasms that can make daily movement and functioning significantly more difficult. Treatment of spasticity in these patients requires a comprehensive approach that includes various therapeutic modalities. Physiotherapy interventions play a key role in the management of spasticity in multiple sclerosis. They are aimed at improving functional ability, reducing pain, increasing range of motion and improving quality of life. Physiotherapy interventions include a wide range of techniques such as kinesitherapy, hydrotherapy, cryo/thermotherapy, shock wave, therapeutic ultrasound, vibration therapy, robotics, biofeedback, correct positioning, use of orthotics, stretching, manual techniques and specialized approaches such as Bobath, Vojta therapy and proprioceptive neuromuscular facilitation. The effectiveness of these interventions may vary depending on the individual characteristics of the patient and the stage of the disease. It is therefore crucial that each patient is assessed and treated individually, with a personalized rehabilitation plan that will best suit their specific needs and goals. A multidisciplinary approach that combines different therapeutic modalities offers the best prospects for reducing spasticity and significantly improving the quality of life of patients with multiple sclerosis.