Introduction and Aim: The study aims to explore the representation of nursing diagnosis in patients with a medical diagnosis of cirrhosis of the liver. With the study should be determine: which are the nursing diagnoses occurred in patients with cirrhosis of the liver; which is the most common nursing diagnosis in patients with cirrhosis of the liver and which are nursing - medical problems (NMP) reported in patients with cirrhosis of the liver. Material and methods: The study was conducted on the random sample of patients at the Department of Gastroenterology and Hepatology, Clinical Hospital Center Split in the period from March to July 2015, using a questionnaire, prepared in cooperation with the mentor. It participated 31 patients. The data from the questionnaire was entered into a Microsoft Excel table to the previously prepared a code plan. For processing was use descriptive statistics. Results: Majority of the patients who suffers from cirrhosis of the liver is alcoholic etiology (61%). The most common age group of patients is between 40-49 years of life. None of the patients were not younger than 41 years is not older than 81 years. The highest number of patients had been hospitalized between 6-10 days. In more than half of respondents have occurred the following nursing diagnosis: reduced of exercise tolerance, deficient intake of food, high risk for tissue damage, high risk for damage respiratory function and high risk for infection. It is not a negligible share of the following nursing diagnosis (48%): increased volume of liquid, self deficit care elimination, insomnia, sleep disorders, impaired body image, and ineffective adherence to health recommendations. The most common nursing diagnosis that occurred in the reduced of exercise tolerance patients in 94% of the respondents. The most represented NMP that occurred in these patients are high risk for bleeding in 68% of subjects and the high risk for shortness of breath in 48% of subjects. Conclusion: Overall, 94% of patients had reduced of exercise tolerance. The most represented NMP was high risk for bleeding in 68% of subjects and the high risk of shortness of breath in 48% of subjects. The study was conducted on a small sample and should be done on a larger sample, in cooperation with the nurses - technicians from Gastroenterologists sections, how would we get relevant information and improve health care in patients with medical diagnosis cirrhosis of the liver.