Treatment of breast cancer depends on the type of tumor and it's features, the location of breast cancer in breast and regional lymphatic drainage and the stage of the disease. Localized treatment modalities such as surgical and radiotherapy or systemic forms of treatment such as chemotherapy, hormone therapy, immunotherapy, and targeted therapy with small molecules can be implemented. Treatment can be performed adjuvantically after surgical treatment to eliminate possible disease micrometastasis, neoadjuvant prior to surgery in the course of reducing disease volume and translating from initially inoperable stage to operable, and primarily for metastatic disease where is treated surgically, exceptionally, for palliative purposes. Radiotherapy is often used as a modality of treatment that uses ionizing radiation. We differentiate the teleradiotherapy that is using the linear accelerator or brachial radiotherapy that treats the breast area using radioligious iridium needle pins. Today, technology is progressing more and more, making it possible for better and more accurate work and better results in the treatment of oncological patients. Conformal radiotherapy, which is today standard, uses CT simulator images transferred to a computerized planning system and enables accurate field and beam radiation shaping. Each member of the radiotherapy team must be responsible for their part of the overall radiotherapy procedure, in accordance with their knowledge and skills, to learn the best possible treatment results with minimal toxicity.