| Abstract | Cilj: Identificirati, opisati i usporediti s drugim istraživanjima čimbenike rizika za razvoj infekcija povezanih sa SVK. Dokazati povezanost broja dana kateterizacije s rizikom za razvoj infekcija povezanih sa SVK.
Metode: Provedeno je retrospektivno istraživanje u koje je bilo uključeno 200 bolesnika odjela Kardiokirurgije KBC Split kojima je na dan operacije, u operacijskoj sali plasiran SVK u venu jugularis. Uvidom u dokumentaciju uzeti su podatci o dobi bolesnika i broju dana kateterizacije. Svaki odstranjeni SVK poslan je na mikrobiološku analizu u mikrobiološki laboratorij KBC Split, zajedno sa uzetom hemokulturom. SVK kod kojeg nije došlo do porasta mikroorganizama na SVK ni hemokulturi smatra se sterilnim, SVK kod kojeg je došlo do porasta mikroorganizama, a da je hemokultura sterilna smatra se koloniziranim, SVK kod kojeg je došlo do porasta mikroorganizama na SVK i hemokulturi smatra se inficiranim.
Rezultati: Od ukupnog broja bolesnika (200) kojima je plasiran SVK u njih 162 (81 %) nije dokazana infekcija povezna sa SVK, u 29 (14,5 %) bolesnika dokazana je kolonizacija SVK, a u 9 (4,5 %) dokazana je infekcija povezana sa SVK. Dokazano je da postoji statistički značajna razlika životne dobi između ispitivanih skupina ( χ2= 6.2; P =0,045). Medijan životne dobi bolesnika bez infekcije za 10 god. je veći nego onih s infekcijom (z = 1,92; P=0,055) na razini značajnosti od 96 %. Nije dokazana statistički značajna razlika između ispitanika bez infekcije i onih s kolonizacijom (z = 1,75; P=0,079). Nije dokazana statistički značajna razlika između ispitanika s infekcije i onih s kolonizacijom (z = 0,481; P=0,499). Postoji statistički značajna razlika medijana broja dana kateterizacije između ispitivanih skupina (χ2= 46,7; P <0,001). Medijan dana kateterizacije svi ispitanika (200) je 6 (3-12). Medijan broja dana kateterizacije za 5 dana je veći kod ispitanika s infekcijom nego kod ispitanika bez infekcije (z = 5,0; P<0,001). Medijan broja dana kateterizacije za 2 dana je veći kod ispitanika s kolonizacijom nego kod ispitanika bez infekcije (z = 4,9; P<0,001). Medijan broja dana kateterizacije za 3 dana je veći kod ispitanika s infekcijom nego kod ispitanika s kolonizacijom (z = 4,9; P<0,0 01).
Zaključak: Istraživanjem smo dokazali da veći broj dana kateterizacije nosi i veći rizik za razvoj infekcije povezane sa SVK. Prisustvo većeg broja čimbenika rizika također povećava rizik za razvoj infekcija povezanih sa SVK. |
| Abstract (english) | Objective: To identify, describe and compare with other studies the risk factors for infection associated with CVC. To prove the correlation between the number of days of catheterization with the risk of infection associated with CVC.
Methods: A retrospective study was conducted which included 200 patients of the department for cardiac surgery KBC Split, who on the day of the operation, in the operating room inserted a CVC in the jugular vein. The following information was taken from the patients documentium: age, day of setting the CVC, day of removal, number of days of catheterization. Each removed CVC was sent for microbiological analysis in the microbiology lab KBC Split, along with the taken blood cultures. The CVC in which there wasn’t an increase of microorganisms in the CVC or blood cultures was considered sterile, while the CVC where there was an increase of microorganisms, but the blood culture was sterile is considered to be colonized, the CVC where there was an increase of microorganisms in the CVC and blood culture was considered to be infected.
Results: Of the total number of patients (200) who had a placed CVC in 162 (81 %) patients there was no proven infection related with CVC, in 29 (14.5 %) patients there was a demonstrated colonization of the CVC, and 9 (4.5 %) patients demonstrated a infection associated with CVC. It has been proven that there is a statistically significant difference in age between the two groups (χ2 = 6.2; P = 0.045). The median age of patients without infection was 10 years larger than those with infection (z = 1.92; P = 0.055) at a significance level of 96 %. There was no significant difference between patients without infection and those with colonization (z = 1.75; P = 0.079). There was no proven significant difference between patients with infection and those with colonization (z = 0.481, P = 0.499). There is a statistically significant difference between the median number of days of catheterization between the two groups (χ2 = 46.7; P <0.001). The median number of days of catheterization for all subjects (200) was 6 (3-12). The median number of days of catheterization was 5 days higher in patients with infection than those without infection (z = 5.0; P <0.001). The median number of days of catheterization was 2 days higher in patients with colonization than those without infection (z = 4.9; P <0.001). The median number of days of catheterization was 3 days higher in patients with infection than those with colonization (z = 4.9; P <0.0 01).
Conclusion: The research proves that a higher number of days of catheterization carries a higher risk for infection associated with CVC. The presence of a large number of risk factors also increases the risk of infection associated with CVC. |
