Title Candida - uzročnik ginekoloških infekcija i infekcija novorođenčadi Title (english) Candida AS A CAUSATIVE AGENT IN GYNECOLOGICAL AND NEONATAL INFECTIONS Author Tomislava Dučić Mentor Vanja Kaliterna (mentor)Committee member Vanja Kaliterna (član povjerenstva)Committee member Diana Aranza (član povjerenstva)Committee member Katarina Šiško Kraljević (predsjednik povjerenstva)Granter University of Split Defense date and country 2018-09-21, Croatia Scientific / art field, BIOMEDICINE AND HEALTHCARE Abstract Candida je dio normalne flore, može kolonizirati kožu, površinu sluznica te adherirati na površinu stranog tijela. Vrste koje najčešće uzrokuju bolesti su: Candida albicans, Candida parapsilosis, Candida glabrata, Candida tropicalis, Candida guilliermondi i Candida lusitaniae.
Gljive (Candida) najčešće uzrokuju kožne i sluznične infekcije. Candida u žena može uzrokovati vulvovaginalnu infekciju praćenu obilnim bijelim iscjetkom te neugodne smetnje, a također se može prenijeti na novorođenče pri porodu. U novorođenčadi je čest nalaz oralne kadidoze s bjelkastim naslagama u ustima koje nisu praćene znakovima sustavne infekcije.
U ovom radu utvrđeno je da je 761 (6.77%) žena bilo pozitivno na gljivu Candida od 11.237 testiranih u rutinskom radu Laboratorija za dijagnostiku infekcija spolnog sustava NZJZ-a. Statistički značajno češće je kandida izolirana u trudnica (p<0,05). Testirano je ukupno 9.345 žena koje nisu bile trudne od kojih je 594 (6,35%) bilo pozitivno na gljivu Candida. Od 1.892 testirane trudnice, njih 167 (8,83%) bilo je pozitivno. Nije postojala statistički značajna razlika u učestalosti izolacije vrsta C.albicans i C.nonalbicans u skupini žena koje nisu bile trudne i trudnica (p>0,05). Od 761 pozitivna izolata, njih 318 (41,8%) bilo je Candida albicans, dok su ostatala 443 (58,2%) pripadala u skupinu Candida nonalbicans.
U rezultatima ovoga rada utvrđeno je da infekcija gljivom Candida nije česta u obriscima spolnog sustava žena koji su testirani u rutinskom radu Laboratorija za dijagnostiku infekcija spolnog sustava, ali ipak treba misliti na mogućnost prijenosa gljive Candida na novorođenčad od majki koje imaju vulvovaginalnu kandidozu, bilo da se radi o infekciji ili samo kolonizaciji.
Ključne riječi: Candida, vulvovaginalna gljivična infekcija, gljivične infekcije novorođenčadi
Abstract (english) Candida is part of a normal flora, it can colonize the skin, mucous membranes and attach to the surface of a foreign body. The most common species that cause diseases are: Candida albicans, Candida parapsilosis, Candida glabrata, Candida tropicalis, Candida guilliermondi and Candida lusitaniae.
Fungi (Candida) most commonly cause skin and mucous infections. In women, Candida can cause vulvovaginal infection followed by abundant white discharge and unpleasant disturbances. It can also be transmitted to a newborn at birth. In newborns, a common clinical finding is oral candidiasis with white secretion in the mouth tahat is not followed by signs of systemic infection.
In the present study, it was found that 761 (6.77%) women were positive for Candida of total 11.237 tested in the routine work of the Laboratory for diagnosis of STIs of Public Health Institute. Candida was statistically more frequent isolated in pregnant women (p <0.05). 9345 non pregnant women were tested, and 594 (6.35%) of them were positive for Candida. Of total 1.892 tested pregnant women, 167 (8.83%) were positive. There was no statistically significant difference in the incidence of isolation of C.albicans and C.nonalbicans between groups (women who were not pregnant and pregnant women) (p> 0.05). From the 761 positive isolates, 318 (41.8%) were species Candida albicans, while 443 (58.2%) were Candida nonalbicans.
In the present study, it is shown that Candida infection in female genital tract is rare, participants were tested in routine work in a laboratory for STI diagnosis, but we need to think on possibility of transferring fungi Candida on newborns from mothers who have vulvovaginal candidiasis, whether infection or colonization.
Keywords: Candida, vulvovaginal fungal infection, fungal infections of newborns
Keywords
Candida
vulvovaginalna gljivična infekcija
gljivične infekcije novorođenčadi (ključne riječi unio urednik)
Keywords (english)
Candida
vulvovaginal fungal infection
fungal infections of newborns (ključne riječi unio zrednik)
Language croatian URN:NBN urn:nbn:hr:176:080883 Study programme Title: Midwifery (university/undergraduate) Type of resource Text File origin Born digital Access conditions Open access Terms of use Created on 2020-05-25 10:04:01
