AIM: To examine the knowledge and attitudes of the students of the Split School of Health and the students of the University Department of health studies in Split towards cardiopulmonary resuscitation. METHOD: 186 examinees participated in this study. This study included 94 students from the University Department of health studies in Split and 92 students from the School of health. The measuring instrument for this research is the anonymous CAEPCR Questionnaire (Nurses' Knowledge and Attitude in the Case of Cardiorespiratory Arrest - Original Spanish), which consists of three parts. The first general part of the questionnaire relates to the demographic characteristics of the examinees. The second part of the questionnaire contains 11 questions on knowledge and the third part of the questionnaire contains 12 questions on the attitudes towards cardiopulmonary resuscitation. RESULTS: We proved a statistically significant difference in the total number of correct answers to the knowledge questions between the university students and school students (Z = 2.96; r = 0.217; P=0.003). If we sum up the correct answers to all 11 questions of “knowledge” in the exam question, we will get meditates total of the correct answers of all respondents together is 6 (Q1-Q3: 5-7; min-max 2-10); in Split Health School students are 6 (Q1-Q3: 5-7; min-max 2-9) and students in the University Department of health studies in Split are 5 (Q1-Q3: 4-6; min-max 2-10). There is statistical significance, a weak negative correlation of the total number of positive responses with the age of the respondents. Spearman's correlation coefficient ρ = -0.195 (P=0.008). The distribution of the total sums of correct answers according to the 5 statistical groups formed is generally differed between institutions. The distribution of examinees according to the Likert scale on questions 2 and 6 about the attitudes has a statistical difference between institutions. CONCLUSION: Considering the obtained results, we have concluded that the level of knowledge is higher with the students of the School of Health, unlike the students of the University Department of Health studies in Split. This result was compounded by the difference in education shown in the curricula. A statistically significant difference in attitudes was only found in questions 2 and 6. Due to the difference in education, in the duration of education and the time elapsed since education, further detailed research on the impact of these factors on knowledge is advised to be investigated.