Lumbar pain syndrome (also known as a low back pain) is a painful experience that many of us have to deal with at least once. This syndrome usually occurs during the most productive period in life and it is followed by reduce ability to work and it requires adequate medical treatment. Because of all the reasons listed above, low back pain should be seen as an public health issue. Ligamentous apparatus injury, paravertebral muscles and facet joints injuries mostly occur bue degenerative disease of spine, or while lifting heavy things, or while doing sudden movements conjoint with rotation. This research paper is about manual techniques which are used to treat low back pain with functional blockade of involved joints. Manual methods and those techniques are helpful in treating dysfunctional neuromuscular spinal disorders, and for reducing pain as well. Diagnostic treatment by McKenzie concept gain insight into the patient's condition and location of interference, eliminating the pain, restores complete function and educates the patient about the proper, protective positions. Manual therapy begins with soft tissue techniques, which help to reduce the pain and also to remove the muscle spasm. Mobilisation techniques used for painful intervertebral discs reduce the functional blockade of involved joints and it helps to establish the full mobility. Manual therapy has been proved as very effective in treating because it includes individual approach, directly treats cause of a problem, it helps to bring people back to work faster. That’s why is more effective than conventional physical therapy (which treats symptoms only). This study shows that extensive exploration with more respondents can get statistically significant results, which may show that manual therapy can be backbone of therapy in solving functional problems of locomotor system.