Pathological changes of the neck can be shown by various imaging modalities, starting from conventional film radiography to modern tomographic images. All changes are noticeable on CT or MR, but again we have modalities such as DSA and DUS that are more optimal for detecting changes in the vertebral arteries. Since the neck is an anatomically complex region, it is important to know from the initial clinical examination which further procedures, ie which further imaging modalities can lead to a diagnosis as soon as possible. Also, we must take into account possible contraindications for certain modalities, such as metal implants in magnetic resonance imaging, but also their positive and negative attributes. Computed tomography (CT) has a high diagnostic value and the best risk-benefit ration, but very few hospital centers use low-dose protocol. Magnetic resonance imaging (MRI) is the 32 best modality for the evaluation of soft tissues, but it is time-consuming and expensive. Ultrasonography is mostly used for the analysis of superficial structures of the neck. DSA is the gold standard for the diagnostic evaluation of carotid and vertebral arteries, but also has shortcomings such as exposure to ionizing radiation.