Summary: Deep venous thrombosis or DVT is manifested by blood clotting in the deep veins of the limbs, most commonly in the lower leg, thigh, or pelvic veins. It occurs in conditions that lead to endothelial damage and dysfunction, worsen venous circulation or in conditions of hypercoagulability. The aim of this paper is to describe DVT and possible complications and consequently the treatments and methods used to prevent DVT. DVT of the lower extremities occurs most often due to impaired venous circulation (in immobilized patients), dysfunction (after a broken leg) or endothelial injury, while deep venous thrombosis of the upper extremities occurs after endothelial injury with cardiac pacemakers, central venous catheter, or intravenous drug addiction. DVT often causes pulmonary embolism, which is a life-threatening condition and therefore the prevention of DVT is of utmost importance. Thrombi consist of fibrin, thrombin and erythrocytes with few platelets (red thrombi). Without treatment, blood clots can spread proximally or embolize over the next few days or both. Common complications that we will describe in detail in the paper are postphlebitis syndrome, chronic venous insufficiency, and the already mentioned pulmonary embolism. It is important to distinguish between diseases that resemble deep vein thrombosis. It is great importance to be able to recognize the signs and symptoms of DVT from which we have non- specific and specific symptoms. DVT develops rapidly and it is very important to learn the procedures ande methods of treatment used in hospitals to save lives and improve the quality of life of patients