Skin as largest human organ is made of three layers epidermis, dermis and subcutaneous fat tissue. Skin serves as intermediary sensor for mechanical, heat and chemical damages and has function to protect. Atopic dermatitis is a chronic inflammatory skin illness that in children is associated with other atopic diseases. It is characterized by pronounced itching, skin redness, dry skin and tendency of frequent symptoms return. The actual cause of the disease is unknown, but the most common manifestation of illness is manifested in countries that are highly developed and industrialized, while far fewer in under developed countries. The genetic heritage is proven and female parent is most common etiology factor. Clinical picture and history are the basis for the diagnosis of atopic dermatitis. In order to confirm the diagnosis of atopic dermatitis there should be three main features and three side-effects of the disease present in the clinical picture. We diagnose allergy treatment for IgE antibody detection, PRIST and RAST, prick test and patch. Treatment of the disease is multidisciplinary and symptomatic and only good co-operation between parents and medical staff will have positive results and will prevent the onset of complications of the disease. Allergens that lead to worsening of the disease need to be avoided. In therapy we use antibiotics, corticosteroids, antihistamines, localimmunomodulators. Very good results in calming the symptoms occur when applying phototherapy, climatotherapy and halotherapy. The skin needs to be constantly nurtured with damp creams. A nurse is the one who teaches patients (their parents or guardians) and provides psychological support that is very important for the course of chronic disease. Anxiety usually occurs as an pleasant emotional state of nervousness and discomfort. The task of the nurses is to provide support to the patients, to show understanding, to create a sense of trust and to encourage them to express their feelings and fears. Continuous training of staff and patients involved in atopic schools is needed, where in addition to new knowledge, they exchange opinions and experiences.