Peripheral arterial occlusive disease is atherosclerosis of the lower extremities, causing their ischemia. Mild peripheral arterial occlusive disease can be asymptomatic or cause intermittent claudication; severe peripheral arterial occlusive disease can cause pain at rest and limb atrophy of the skin, hair loss, cyanosis, ischemic ulcers and gangrene. Diagnosis is based on medical history, physical examination and measurement of ankle brachial index. Mild peripheral arterial occlusive disease is treated with the influence of the risk factors, exercise, antiplatelet drugs. Severe peripheral arterial occlusive disease usually requires angioplasty, bypass surgery or amputation. The prognosis is generally good with treatment, although the mortality rate is relatively high due to coronary or cerebrovascular disease because patients often have both at the same time. In case of need for amputation, the nurse must provide a strong psychological support to the patient. She has to wield a high level of knowledge and skills. The focus of health care in this period must be focused on creating patient confidence, reduce fear and acceptance of life without limbs. In the process of treating the patient becomes an equal member of the health care team in providing health care. The doctor and nurse agreed and planned health care together with the patient. This kind of care instills confidence and safety in patients