Title Usporedba kvalitete života bolesnika oboljelih od psorijaze prije i nakon uvođenja biološke terapije
Title (english) COMPARISON OF THE QUALITY OF LIFE OF PATIENTS WITH PSORIASIS BEFORE AND AFTER THE INTRODUCTION OF BIOLOGICAL THERAPY
Author Anita Bikić
Mentor Neira Puizina Ivić (mentor)
Committee member Rahela Orlandini (predsjednik povjerenstva)
Committee member Tonći Stipić (član povjerenstva)
Committee member Neira Puizina Ivić (član povjerenstva)
Granter University of Split (University Department of Health Studies) Split
Defense date and country 2018-09-26, Croatia
Scientific / art field, discipline and subdiscipline BIOMEDICINE AND HEALTHCARE Clinical Medical Sciences
Abstract Cilj: Ciljevi istraţivanja su istraţiti ukupan broj psorijatičnih bolesnika liječenih biološkom terapijom te razdiobu po dobi i spolu bolesnika. TakoĎer istraţiti koliko su dugo bolovali od psorijaze prije uvoĎenja terapije, usporediti kvalitetu ţivota prije i poslije uvoĎenja biloške terapije. Ispitanici: Ispitanici su činili uzorak bolesnika liječenih u dermatovenerološkoj poliklinici Klinike za koţne i spolne bolesti KBC Split. Sudjelovalo je 95 ispitanika od čega su 62 muškarca i 33 ţene. Metode: Na ispitanicima je primijenjen upitnik Klinike za dermatovenerologiju o dermatološkom indeksu kvalitete ţivota te upitnik demografskih podataka o ispitanicima. U svrhu istraţivanja korišten je dermatološki indeks kvalitete ţivota DQLI (Dermatological Quality of Life Index). DQLI je ljestvica kojom se vrednuje utjecaj psorijaze na svakodnevni ţivot bolesnika; fizički, socijalni i psihički. Podatci o broju oboljelih te razdioba prema dobi prikazani su apsolutnim brojem i postotkom. Podatke smo unijeli u Excel tablicu, a zatim analizirali u statističkom paketu IBM SPSS v 23.U obradi smo koristili χ2 test, Mann-Whitney U test i Wilcoxon test. Rezultate smo interpretirali na razini značajnosti p<0,05. Rezultati:. U provedenom istraţivanju dokazan utjecaj psorijaze na kvalitetu ţivota oboljelih. Medijan broja bodova u svezi izgleda iz upitnika nakon terapije pao je za 3 boda u ţena (z=5,1; p<0,001) i za 2 boda u muškaraca (z=6,9; p<0,001) u odnosu na broj bodova prije terapije. Ţene iako kraćeg trajanja bolesti osjetljivije su na izgled. Što se tiče pitanja pitanje vezao za osobne odnose, medijan odgovora na ovo pitanje prije biološke terapije iznosio je 3 (min-maks:0-3) a nakon terapije 0 (min-maks: 0-2). Došlo je pada medijana za 3 (z=6,9; p<0,001. Zaključak: Prije terapije više od 74% bolesnika je svakom od 10 pitanja iz DLQI upitnika dodijelilo 3 boda što znači da je bolest vrlo mnogo utjecala na lošu kvalitetu ţivota u svakom segmentu. Nakon terapije 94% bolesnika je svakom od 10 pitanja dodijelilo 0 bodova što znači jako dobru kvalitetu ţivota u svakom segmentu
Ključne riječi: psoriasis vulgaris, DQLI (Dermatological Quality of Life Index), biološki lijekovi.
Abstract (english) Objective: The aims of the study are to investigate the total number of psoriatic patients treated with biological therapy and the distribution by age and sex of patients. Also investigate how long they have been suffering from psoriasis before introducing therapy, compare quality of life before and after the introduction of herbal therapy. Respondents: Respondents made a sample of patients treated in the dermatovenerology clinic of the Clinic for Skin and Sexual Diseases KBC Split. 95 respondents took part, of which 62 were men and 33 women. Methods: The questionnaire of the Clinic for Dermatovenerology on the dermatological index of quality of life was applied to the respondents and a questionnaire on the demographic data on respondents. For the purpose of research, the dermatological quality index of life quality DQLI (Dermatological Quality of Life Index) was used. DQLI is a scale that evaluates the impact of psoriasis on the everyday lives of patients; physically, socially and mentally. Data on the number of patients and age distribution according to age are shown with an absolute number and percentage. Data was entered into the Excel table, and then analyzed in the IBM SPSS statistical package at 23. In the processing we used the χ2 test, the Mann-Whitney U test, and the Wilcoxon test. The results were interpreted at the level of significance p <0.05. Results:. In the conducted research, the influence of psoriasis on the quality of life of patients has been proven. The median number of points in terms of the questionnaire after treatment has dropped by 3 points in women (z = 5.1, p <0.001) and 2 points in men (z = 6.9; p <0.001) in relation to the number of points before therapy. Women, although shorter the duration of the disease are more susceptible to appearance. As for the question of the question of personal relationships, the median answer to this question before biological therapy was 3 (min-max: 0-3) and after therapy 0 (min-max: 0-2). There was a drop in the median by 3 (z = 6.9; p <0.001. Conclusion: Prior to therapy, more than 74% of patients assigned 3 of the 10 questions from the DLQI questionnaire 3 points, which means that the disease very much affected the poor quality of life in each segment. After the treatment, 94% of the patients assigned 0 points to each of the 10 questions, which means a very good quality of life in each segment.
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Key words: psoriasis vulgaris, DQLI (Dermatological Quality of Life Index), biological drugs.
Keywords
psoriasis vulgaris
DQLI (Dermatological Quality of Life Index)
biološki lijekovi (ključne riječi unio urednik)
Keywords (english)
psoriasis vulgaris
DQLI (Dermatological Quality of Life Index)
biological drugs (ključne riječi unio urednik)
Language croatian
URN:NBN urn:nbn:hr:176:366103
Study programme Title: Nursing (university/graduate) Study programme type: university Study level: graduate Academic / professional title: magistar/magistra sestrinstva (magistar/magistra sestrinstva)
Type of resource Text
File origin Born digital
Access conditions Open access
Terms of use
Created on 2020-05-29 10:19:18